This repository only holds raw data as the processed data are available through the publication linked to this dataset: Krishna et al 2025 Analyst. In that publication data have been processed as it follows:
Mass spectra were processed either directly in Masslynx v4.2 (respective releases as above) or opened in Masslynx and exported into mMass, an open-source mass spectral analysis platform. MSI experiments were set up using DESI Method Editor v2.3.8 for the Xevo TQ-XS, and Quartz (v2.12.1, v2.7.1) for cIMS, and MRT respectively.
All the DESI-cIMS and MALDI-MRT imaging experiments were processed and visualised using HDI v1.8 (Waters Corporation, Wilmslow UK) with the following settings: MS resolution of (100,000 for cIMS, and 200,000 for MRT), m/z window of (0.02 for cIMS, and 0.005 for MRT), and the number of most intense peaks set to 1000. The DESI-Xevo TQ-XS MRM images were auto processed from Masslynx and visualised in HDI v1.8. . Except for those generated by the Xevo TQ-XS , all the images were TIC (Total Ion Count), normalised unless specified otherwise. Relevant regions of interests (ROI) were exported to MassLynx™ v4.2 (respective releases as above) software for spectral analysis.